Cortical Tubers Without Neurological Symptoms: An Uncommon Case of Tuberous Sclerosis Complex

Abstract

Tuberous Sclerosis Complex (TSC) is a genetic disorder and rare type of neurocutaneous syndrome characterized by development of benign nodules in various organs of the body including the brain, skin, kidneys, and heart. Epilepsy and mental retardation are common neurological manifestations of this disorder in most cases. However, cases with isolated cutaneous findings and preserved neurological function are rare and have not been well reported in the literature. The purpose of this case report is to highlight the phenotypic variation in the TSC phenotype and to stress the need for increased clinical vigilance in atypical cases.