Archives

  • Patterns of Femoral fractures
    Vol. 5 No. 2 (2024)

  • Metastatic Ocular Melanoma to the Breast and Axillary Lymph Nodes: An Unusual Case Presentation
    Vol. 5 No. 1 (2024)

  • Vol. 6 No. 2 (2025)

    The volume Six, Issue 18, number Two, the second quarter issue of 2025 goes with the title: “Renal Resistivity Index (RRI) in Extent of Renal Damage Among Sickle Cell Patients” where the authors critically looked at renal resistivity index and its relationship with other markers of renal damage in sickle cell disease patients. They found that: an  inverse but non-significant correlation was observed between RRI and estimated Glomerular Filtration Rate (eGFR); a significant association between elevated RRI and history of blood transfusion in the past year; and no significant associations between RRI and bone pain crises, hospitalisation, or proteinuria. They then came to the conclusion that elevated RRI is common in SCD patients and may reflect early renal vascular changes not detectable by eGFR alone and hence can serve as an early marker of disease severity.

    In another study authors lloked at the institutional patterns of recurrent goitre where the researchers carried out a comprehensive retrospective analysis of thyroidectomy outcomes from two referal health centres. They found that: A total of 88.2% of recurrences occurred after initial subtotal thyroidectomy (p<0.001), highlighting the inadequacy of this procedure. The recurrences ranged from 1 to 12 years post operation. And that Clinical presentations were predominantly in the form of simple nodular goitre (61.8%), while 23.5% of pathologic specimens presented with unsuspected malignancies, which were predominantly papillary carcinoma. Reoperations were completion  thyroidectomy (35.3%) and repeat subtotal operations (29.4%), with an overall complication rate of 36.4%. They eventually concluded that there is need for policy changes toward definitive surgical treatment of benign multinodular goitre in low-resource settings with a focus on prevention of unnecessary reoperations through enhanced initial treatment.

    Also in another study, researchers assessed a case of fibrocystic change in a male breast. They noted that although this lesion is common in female breast, it is exremely rare in male breast and hence physicians should be extremely vigilant and look out for it to avoid misdiagnosis and over-treatment.

    A case of foreign-body induced abdominal perforation in a vagrant patient with Schizophrenia was also presented. Exploratory laparotomy revealed multiple foreign bodies in the stomach, including four and six-inch nails, currency notes, padlock keys, and plastic items. Postoperative psychiatric management led to symptom control with a switch to long acting injectable antipsychotics to improve adherence. The patient showed significant clinical and behavioural improvement and had remained in remission six months after his discharge and had been regular on follow-up.

    Professor Michael Simidele Odimayo

    Editor-In-Chief

    30th June, 2025 

  • Vol. 6 No. 1 (2025)

    FOREWORD

    The volume Six, Issue 17, number One, the first quarter issue of 2025 goes with the title   “Cortical Tubers Without Neurological Symptoms: An Uncommon Case of Tuberous Sclerosis Complex”. The authors stressed that not all cases of Tuberous Sclerosis Complex (TSC) present with all the classical features as there are also phenotypic non-classical variants of the same disease. That it is a rare genetic neurocutaneous syndrome often characterized by presence of benign nodules in different parts of the body including brain. A thorough clinical and radiological examinations will help diligent physicians to identify non-classical phenotypic variants.

    In another study researchers x-rayed Primary Health Care Under One Roof (PHCUOR) In Nigeria in retrospect in order to ascertain the successes and failures attained so far. And they came to the conclusion that the policy which is backed by law has failed to attained the desired impact due to myriad of challenges. Some of which include infrastructural constraints, inadequacy of staff to drive it, and unwillingness of the relevant health personnel to show understanding, work as a team to ensure its success.

    Hydroxyurea has been reported to be effective in the management of patients with sickle cell disease and in this vein a team of researchers set out to evaluate the clinical and laboratory outcomes of children with SCA on hydroxyurea therapy. They found that Hydroxyurea therapy significantly reduced the frequency of vaso-occlusive crises (mean reduction from 7.70 to 1.91, p = .000), hospital admissions (mean reduction from 2.60 to 0.84, p = .000), and blood transfusions (mean reduction from 1.51 to 0.40, p = .005) along with significant decrease in hospital stay duration.

    Professor Michael Simidele Odimayo

    Editor-In-Chief

    31st March, 2025